Nautilus

The Family That Couldn’t Say Hippopotamus

There is a family living in Britain, known only as the KE family, with a few members that can’t quite say words like “hippopotamus.” They know the words, but can’t get their mouth positions quite right, so their speech comes out garbled. Some family members have a hard time saying words in the right order, and others have trouble reciting words that begin with the same letter. Multiple generations of the family have similar language difficulties, suggesting a genetic basis for their disorder.

In the early 2000s, Oxford University geneticists Anthony Monaco, Simon Fisher, and their colleagues found the culprit: KE family members had a rare mutation in a gene called FOXP2.1 The mutation was subtle—only one nucleotide removed from the typical FOXP2 sequence—but the resulting language impairment was substantial. That meant there was probably something about the normal FOXP2 gene that helped enable fluent speech. In the wake of this finding, FOXP2 was trumpeted in the press as a “grammar gene” and a “language gene.” 

The public’s “language gene” assumption seemed to fit well with certain long-standing theories about the origins of language. In the mid-1960s, linguist Noam Chomsky proposed that the human brain is equipped with a’s John Gliedman in a 1983 interview.

You’re reading a preview, subscribe to read more.

More from Nautilus

Nautilus4 min read
How Sound Rules Life Underwater
1 Sound travels very differently in water than air. Like most humans, I assumed that sound didn’t work well in water. After all, Jacques Cousteau himself called the ocean the “silent world.” I thought, beyond whales, aquatic animals must not use soun
Nautilus4 min read
The Most Unlikely Migration
In late summer, as the days shorten and begin to cool, the marmalade hoverfly begins to prepare her body for the long journey ahead. Her flight muscles strengthen, her eyesight sharpens, and her immune system bulks up until she is no longer a frail m
Nautilus8 min read
Life Lessons from Hell-House Venus
Hold a grain of sand up to the night sky at arm’s length. There are thousands of galaxies in that miniscule fraction of the heavens. Galaxies like ours hold hundreds of billions of stars—a good portion of which host planets. And a number of these are

Related Books & Audiobooks