Miniature human brains grow for months when implanted in mice skulls
Scientists have successfully implanted human mini brains into the cortices of mice, a significant advance in organoid research.
The mice behaved just like others of their kind, as far as scientists could tell, and they also looked the same — except for the human mini brain that had been implanted into each rodent’s own cortex, made visible by a little clear cover replacing part of their skull.
The on Monday by scientists at the Salk Institute is the first publication describing the successful implant of human cerebral organoids into the brains of another species, with the host brain supplying the lentil-sized mini cerebrums with enough blood and nutrients to keep to understand human brain development and test whether the tiny entities might one day serve as cortical , replacing regions of the brain that have been injured or failed to develop normally.
