*Joint senior co-authors.
Dermatology Department (E J Tarín-Vicente MD, M Agud-Dios MD, J Arroyo-Andrés MD, L Calderón-Lozano MD, E Gil-Cruz MD, B González-Rodríguez MD, C Gutiérrez-Collar MD, J Montero-Menárguez MD, S I Palencia-Pérez PhD, C A Rubio-Muñiz MD, A Wang MD, Prof P L Ortiz-Romero PhD) and Microbiology Department (M D Folgueira PhD, P López-Roa PhD, M de los Ángeles Meléndez PhD, I Muñoz-Gallego PhD, A Pérez-Rivilla PhD), Hospital Universitario 12 de Octubre, Madrid, Spain; Skin Neglected Diseases and Sexually Transmitted Infections Section (A Alemany MD, M Ubals MD, C Suñer PhD, M Vall PhD, C Galván-Casas MD, O Mitjà PhD) and Infectious Diseases Department (R Paredes PhD, J M Cabrera MD, P Coll MD, Á Rivero MD), University Hospital Germans Trias i Pujol, Badalona, Spain; Fight Infectious Diseases Foundation, Badalona, Spain (A Alemany, M Ubals, C Suñer, J M Cabrera, P Coll, Á Rivero, M Vall, C Galván-Casas, O Mitjà, R Paredes); Department of Dermatology, Hospital Universitario de Móstoles, Madrid, Spain (C Galván-Casas); Microbiology Department (A Antón PhD, M Piñana MD) and Infectious Diseases Department (M Arando PhD, V Descalzo MD, J N García-Pérez MD), Hospital Universitari Vall d’Hebron, Barcelona, Spain; Microbiology Department, Clinical Laboratory North Metropolitan Area, University Hospital Germans Trias I Pujol, Badalona, Spain (C Casañ PhD, Á Hernández-Rodríguez PhD, A Ramirez MD); BCN Checkpoint, Projecte dels NOMS—Hispanosida, Barcelona, Spain (J M Cabrera, P Coll, Á Rivero); Research Institute Hospital i+12, Madrid, Spain (M D Folgueira, P López-Roa, M de los Ángeles Meléndez, I Muñoz-Gallego, S I Palencia-Pérez, A Pérez-Rivilla, Prof P L Ortiz-Romero); Department of Medicine, School of Medicine, Complutense University of Madrid, Madrid, Spain (M D Folgueira, S I Palencia-Pérez, A Pérez-Rivilla, Prof P L Ortiz-Romero); Department of Genetics and Microbiology, Autonomous University of Barcelona, Barcelona, Spain (Á Hernández-Rodríguez); IrsiCaixa AIDS Research Institute, Badalona, Spain (R Paredes); Direcció d’Atenció Primària—Metropolitana Nord, Sabadell, Catalonia, Spain (N Prat MD); Radiology Department, Hospital Universitario La Paz, Madrid, Spain (K S Acosta-Velásquez MD); Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK (M Marks PhD); Hospital for Tropical Diseases, London, UK (M Marks); Division of Infection and Immunity, University College London, London, UK (M Marks); Universitat de Vic-Universitat Central de Catalunya (UVIC-UCC), Vic, Spain (O Mitjà); School of Medicine and Health Sciences, University of Papua New Guinea, Port Moresby, Papua New Guinea (O Mitjà)
Correspondence to:
Dr Oriol Mitjà, Skin Neglected Diseases and Sexually Transmitted Infections Section, University Hospital Germans Trias i Pujol, Badalona, Spain oriolmitja@hotmail.com
© 2022 Elsevier Ltd. All rights reserved.
SUMMARY
Background In May, 2022, several European countries reported autochthonous cases of monkeypox, which rapidly spread globally. Early reports suggest atypical presentations. We aimed to investigate clinical and virological characteristics of cases of human monkeypox in Spain.
This multicentre, prospective, observational cohort study was done in three sexual health clinics in Madrid and Barcelona, Spain. We enrolled all consecutive patients with laboratory-confirmed monkeypox from May 11 to June 29, 2022. Participants were offered lesion, anal, and oropharynx swabs for PCR testing. Participant data were collected by means of interviews conducted by dermatologists or specialists in sexually transmitted infections and were recorded using a standard case report form. Outcomes assessed in all participants with a confirmed diagnosis were demographics, smallpox vaccination, HIV status, exposure to someone with monkeypox, travel,
