IT HAS BEEN a long time—decades, really—since Big Skin Care has delivered a clinically reliable way to reverse signs of aging. Since 1971, when topical retinol was found to blur wrinkles and dark spots, the vitamin A derivative has been treated as antiaging's gold standard. Never mind that its side effects can include redness and even mild peeling; what's a little irritation in the pursuit of a younger-looking you?
Lately, though, several companies have started offering serums and creams that claim to regenerate skin's youthful function and appearance, rather than resurface it with harsh active ingredients. They all tout painstaking research suggesting they interrupt cellular senescence, the phenomenon that occurs toward the end of all cells' life