Unavailable
Unavailable
Unavailable
Audiobook
Frances Oldham Kelsey, the FDA, and the Battle against Thalidomide
Written by Cheryl Krasnick Warsh
Rating: 0 out of 5 stars
()
Currently unavailable
Currently unavailable
About this audiobook
The Woman Scientist who saved Americans from thalidomide In the early 1960s, Dr. Frances Oldham Kelsey of the U.S. Food and Drug Administration became one of the most celebrated women in America when she prevented a deadly sedative from entering the U.S. market. A Canadian-born pharmacologist and physician, Kelsey saved countless Americans from the devastating side effects of thalidomide, a drug routinely given to pregnant women to prevent morning sickness. As the FDA medical officer charged with reviewing Merrell Pharmaceutical's application for approval in 1960-61, Kelsey was unconvinced that there was sufficient evidence of the drug's efficacy and safety. Despite substantial pressure, she held her ground for nineteen months while the extent of the drug's worldwide damage became known-thousands of stillborn babies, as well as at least 10,000 children across 46 countries born with severe deformities such as missing limbs, arms and legs that resembled flippers, and improperly developed eyes, ears, and other organs. As a result of Kelsey's efforts, thalidomide was never sold in the United States. The incident led Congress to pass the 1962 Drug Amendment, which fundamentally changed drug regulation in America. Those regulations, still in force today, required pharmaceutical companies to conduct phased clinical trials, obtain informed consent from participants in drug testing, and warn the FDA of adverse effects, and it granted the FDA important controls over prescription-drug advertising. One of a small minority of women to earn an advanced degree in science in the 1930s, Kelsey faced challenges that resonate with women scientists to this day. Revered by the public as a “good mother of science,” she went on to act as a formidable gatekeeper against other suspect drugs, such as diesthylstilbestrol (DES) and laetrile. As part of the team that tested anti-malarial drugs on prisoner volunteers during World War II, she later was instrumental in the formulation of ethical protocols for drug testing on prisoners and the vulnerable, including the elderly and children. Yet behind the public adulation, she faced professional jealousies and glass ceilings, political interference with FDA's actions, and ongoing hostility from pharmaceutical industry officials. She was sustained and supported by family and friends, co-workers and mentors, and a lifetime commitment to good science. Based upon FDA archival records, private family papers, and interviews with family and colleagues, this biography brings to light the efforts and legacy of a pioneering woman of science whose contributions are still influential today.
Unavailable
Related to Frances Oldham Kelsey, the FDA, and the Battle against Thalidomide
Related audiobooks
Frances Oldham Kelsey, the FDA, and the Battle Against Thalidomide Rating: 0 out of 5 stars0 ratingsDrugs and the FDA: Safety, Efficacy, and the Public's Trust Rating: 0 out of 5 stars0 ratingsSummary of Mikkael A. Sekeres's Drugs and the FDA Rating: 0 out of 5 stars0 ratingsBody and Soul: The Black Panther Party and the Fight Against Medical Discrimination Rating: 5 out of 5 stars5/5Summary, Analysis & Review of Ty Bollinger's The Truth About Cancer Rating: 5 out of 5 stars5/5Sex Cells: The Fight to Overcome Bias and Discrimination in Women’s Healthcare Rating: 0 out of 5 stars0 ratingsThe Gerson Therapy: The Proven Nutritional Program for Cancer and Other Illnesses Rating: 4 out of 5 stars4/5Hidden Heroes in Medicine Rating: 0 out of 5 stars0 ratingsPure, White and Deadly: How Sugar Is Killing Us and What We Can Do to Stop It Rating: 5 out of 5 stars5/5A New War on Cancer: The Unlikely Heroes Revolutionizing Prevention Rating: 0 out of 5 stars0 ratingsWhen Abortion Was a Crime: Women, Medicine, and Law in the United States, 1867-1973 Rating: 0 out of 5 stars0 ratingsRebel Health: A Field Guide to the Patient-Led Revolution in Medical Care Rating: 0 out of 5 stars0 ratingsStrange Trips: Science, Culture, and the Regulation of Drugs Rating: 0 out of 5 stars0 ratingsLet America Live Rating: 4 out of 5 stars4/5Summary of Robert F. Kennedy Jr.'s The Real Anthony Fauci Rating: 0 out of 5 stars0 ratingsBlack Man in a White Coat: A Doctor's Reflections on Race and Medicine Rating: 4 out of 5 stars4/5Cells Are the New Cure: The Cutting-Edge Medical Breakthroughs That Are Transforming Our Health Rating: 4 out of 5 stars4/5The Cancer Code: A Revolutionary New Understanding of a Medical Mystery Rating: 5 out of 5 stars5/5Mastering Fear: Harness Emotion to Achieve Excellence in Work, Health, and Relationships Rating: 5 out of 5 stars5/5Medical Bondage: Race, Gender, and the Origins of American Gynecology Rating: 5 out of 5 stars5/5Psychonauts: Drugs and the Making of the Modern Mind Rating: 0 out of 5 stars0 ratingsSubjected to Science: Human Experimentation in America before the Second World War Rating: 0 out of 5 stars0 ratingsSummary of Thomas E. Woods and Jay Bhattacharya's Diary of a Psychosis Rating: 0 out of 5 stars0 ratingsNATIVE AMERICAN HERBAL RECIPES: Traditional Healing Plants and Medicinal Remedies (2023 Guide for Beginners) Rating: 3 out of 5 stars3/5Dispatches from the AIDS Pandemic: A Public Health Story Rating: 5 out of 5 stars5/5Poisoned: The True Story of the Deadly E. Coli Outbreak That Changed the Way Americans Eat Rating: 5 out of 5 stars5/5
Law For You
We Were Once a Family: A Story of Love, Death, and Child Removal in America Rating: 4 out of 5 stars4/5Sweet Taste of Liberty: A True Story of Slavery and Restitution in America Rating: 5 out of 5 stars5/5Win Your Case: How to Present, Persuade, and Prevail--Every Place, Every Time Rating: 5 out of 5 stars5/5The Law of Law School: The Essential Guide for First-Year Law Students Rating: 5 out of 5 stars5/5By Hands Now Known: Jim Crow's Legal Executioners Rating: 5 out of 5 stars5/5The End of Policing Rating: 4 out of 5 stars4/5Arrest-Proof Yourself: Second Edition Rating: 4 out of 5 stars4/5Whoever Fights Monsters: My Twenty Years Tracking Serial Killers for the FBI Rating: 4 out of 5 stars4/5Covered with Night: A Story of Murder and Indigenous Justice in Early America Rating: 4 out of 5 stars4/5Estate & Trust Administration For Dummies Rating: 3 out of 5 stars3/5The Dark Net: Inside the Digital Underworld Rating: 4 out of 5 stars4/5Six Women of Salem: The Untold Story of the Accused and Their Accusers in the Salem Witch Trials Rating: 4 out of 5 stars4/5When Harry Became Sally: Responding to the Transgender Moment Rating: 4 out of 5 stars4/5Three Felonies A Day: How the Feds Target the Innocent Rating: 4 out of 5 stars4/5The Sewing Girl's Tale: A Story of Crime and Consequences in Revolutionary America Rating: 4 out of 5 stars4/5On Account of Race: The Supreme Court, White Supremacy, and the Ravaging of African American Voting Rights Rating: 4 out of 5 stars4/5The Invention of Murder: How the Victorians Revelled in Death and Detection and Created Modern Crime Rating: 4 out of 5 stars4/5Jews Don’t Count Rating: 4 out of 5 stars4/5The Executive Juris Doctor: Learn to Think Like a Lawyer Rating: 4 out of 5 stars4/5The Color of Money: Black Banks and the Racial Wealth Gap Rating: 5 out of 5 stars5/5Norco '80: The True Story of the Most Spectacular Bank Robbery in American History Rating: 4 out of 5 stars4/5Forensics: What Bugs, Burns, Prints, DNA, and More Tell Us about Crime Rating: 4 out of 5 stars4/5Limited Liability Companies For Dummies: 3rd Edition Rating: 4 out of 5 stars4/5Law School Confidential: A Complete Guide to the Law School Experience: By Students, for Students Rating: 4 out of 5 stars4/5Family Trusts: A Guide for Beneficiaries, Trustees, Trust Protectors, and Trust Creators Rating: 5 out of 5 stars5/5
Reviews for Frances Oldham Kelsey, the FDA, and the Battle against Thalidomide
Rating: 0 out of 5 stars
0 ratings
0 ratings0 reviews