Keeping Your Child Healthy in a Germ-Filled World: A Guide for Parents

By Athena P. Kourtis

A “well written and easily comprehended” guide to the microbes in our midst—and how to protect kids from infections (Pediatric Infectious Disease Journal).

We’re all too aware that the world is full of germs—viruses old and new, parasites, fungi, bacteria that sometimes evolve into antibiotic-resistant superbugs. But the truth is that while infections are harmful, not all germs are bad. In fact, some of them we can’t live without.

In this book a pediatrician who specializes in infectious diseases gives parents the clear information they need to keep their families healthy—without panicking or going overboard. Dr. Athena P. Kourtis sorts through topics including antibiotics, vaccines, hygiene, health foods, and home remedies, and identifies which rules to follow—and which ones to ignore. She says:

• No to overprotecting your children from germs
• No to antimicrobial soaps and cleaning products at home
• No to over-prescribed antibiotics
• Yes to strategic hand washing
• Yes to being conscious of germs and the pathways they use
• Yes to vaccines

She offers tips for protecting children at home, in school, at meals, on the playground, on trips, while playing sports—and answers questions that commonly worry parents. How many times should you wash prewashed spinach? (At least twice.) Does getting enough sleep help fight infection? (Yes.) Are pre-sliced foods more likely to spread infection? (They are.) This comprehensive guide is the first step in helping you and your child stay afloat in the microbial sea.

• Language: English
• Publisher: Open Road Integrated Media
• Release date: Oct 1, 2011
• ISBN: 9781421402826

Book preview

Keeping Your Child Healthy in a Germ-Filled World

A JOHNS HOPKINS PRESS HEALTH BOOK

Keeping Your Child Healthy in a Germ-Filled World

A GUIDE for PARENTS

Athena P. Kourtis, M.D., Ph.D., M.P.H.

Note to the reader: This book describes how to help prevent infections in children in general. It was not written about your child. You should obtain the services of a competent professional whenever you need medical or other specific advice.

Dr. Kourtis’s work was performed outside the scope of her employment as a U.S. government employee. Her work represents her personal and professional views and not necessarily those of the U.S. Centers for Disease Control and Prevention.

© 2011 Athena P. Kourtis

All rights reserved. Published 2011

Printed in the United States of America on acid-free paper

2 4 6 8 9 7 5 3 1

The Johns Hopkins University Press

2715 North Charles Street

Baltimore, Maryland 21218-4363

www.press.jhu.edu

Library of Congress Cataloging-in-Publication Data

Kourtis, Athena P.

Keeping your child healthy in a germ-filled world : a guide for parents / Athena P. Kourtis.

p. cm. (A Johns Hopkins Press health book)

Includes bibliographical references and index.

ISBN-13: 978-1-4214-0211-6 (hardcover : alk. paper)

ISBN-13: 978-1-4214-0212-3 (pbk. : alk. paper)

ISBN-10: 1-4214-0211-4 (hardcover : alk. paper)

ISBN-10: 1-4214-0212-2 (pbk. : alk. paper)

1. Self-care, Health—Popular works. 2. Microorganisms—Popular works. I. Title.

RA776.95.K68 2011

613—dc22      2011004100

A catalog record for this book is available from the British Library.

Illustrations by Elizabeth Allen

Special discounts are available for bulk purchases of this book.

For more information, please contact Special Sales

at 410-516-6936 or [e-mail].

The Johns Hopkins University Press uses environmentally friendly

book materials, including recycled text paper that is composed of at

least 30 percent post-consumer waste, whenever possible.

To Alexander,

and to Peter and Constantine,

the three Greats in my life!

"The physician must … have two special objects in view

with regard to disease, namely, to do good or to do no harm."

—Hippocrates, Epidemics, fifth century BC

Contents

Preface

Acknowledgments

When Germs and People Interact: An Introduction

PART I Which Germs Where?

1 I’m Hungry! Food-Borne Germs and Food Preparation Safety

2 A, B, C and 1, 2, 3: Common Germs at Day Care and School

3 Swim, Ski, or Wrestle: Germs Encountered When Playing Sports

4 Fur, Feathers, and Fangs: Germs from Pets and Other Animals

5 The Great Outdoors: Germs in the Garden, at the Campground, on the Farm, and at the Beach

6 Close to Home and Overseas: Tips for Avoiding Germs When You Travel

7 Sexually Transmitted Infections, Tattoos, and Piercings: Helping Teenagers Navigate Germs Safely

PART II Our Defenses against Germs

8 Taking Medicine: The Use and Misuse of Antibiotics

9 The Miracle of Modern Prevention: Vaccine Safety and Effectiveness

10 Baby’s on the Way: Protect Your Unborn Baby with a Healthy Pregnancy

11 Bonding with Your Baby: The Benefits of Breastfeeding

12 Supplements, Herbs, Organic Produce, and Probiotics: Do They Protect You from Germs?

13 Wash Your Hands! Personal and Household Hygiene for the Twenty-first Century

14 Myths and Truths: Does Science Back Up Traditional Wisdom about Preventing Infections?

Afterword

Trustworthy Web Resources

Selected Bibliography

Index

Preface

When you hold this book in your hands, the last thing on your mind, I am sure, is the number of germs moving from your hands to its surface. Germs are microscopic organisms present everywhere: in the air, on the ground, in water, on plants and animals, in the human body. They live in tropical and polar climates, near volcanoes and hot springs, with or without oxygen.

Since the nineteenth century, we have known that some germs cause diseases—the infectious diseases. Around the end of the twentieth century, however, scientists began to understand that germs also cause chronic diseases, such as stomach ulcers and some types of cancer. New scientific evidence has started to connect germs with even more diseases, including atherosclerosis, diabetes, some forms of arthritis, and neuropsychiatric conditions. However, not all germs are enemies. Even though some germs cause disease in humans, animals, and plants, many of them are necessary for our health. In fact, we would not be able to exist without them.

The relationship between humans and germs is complex and fragile. They can damage our health—even kill us—but we need them for our very existence. Since we cannot eliminate all germs (and we do not want to), how can we live healthily with them? What should we do to protect ourselves and our children from germs, without endangering our health from the harmful consequences of our protective measures? Should we clean our homes? Should we vaccinate our children? Should we use antibiotics? How about antibacterial soaps? Information piles up as the media and the Internet step in to offer (sometimes conflicting) advice.

Inspired by the questions of my little patients’ parents, I wrote this book to help you sift through the media information you receive daily. As a pediatrician, I have the privilege of serving my patients—children and their families—and I hear the questions and see the worries parents have about their children’s health. However, I also see the extent of misinformation that is circulated: some parents believe that antibiotics are a cure-all, other parents have misgivings about vaccines, and still others fall prey to the wide promotion of products and ideas with no scientific backing. As an infectious diseases specialist, I see some of the more serious cases of infectious diseases in children, as well as nosocomial infections (those acquired in the hospital) and infections caused by germs that are resistant to antibiotics. As a mother, I know firsthand what concerns parents and what information they truly need to know.

It is my mission to help educate parents on infections and their prevention as related to their children’s health. I begin with an introduction to germs to give you some background about them and their ongoing relationship with humans. The first part of this book describes what germs your children are likely to encounter through their various activities. I describe how these germs spread and multiply and how they make us sick. Understanding how germs spread and the pathways they use is the first step to preventing infections.

The second part of this book discusses the means we have today for preventing infections: new ways of practicing hygiene for ourselves and for our home, whether we should use antimicrobial soaps and cleaning products, and the very important preventive strategy offered by vaccines. Part II also explores the proper use of antibiotics, prevention of infections during pregnancy, the benefits of breastfeeding, and whether our children’s immune systems require food supplements or herbs. Probiotics is a new and evolving field; I describe what we know about these live microorganisms that some people take to improve their health. Finally, I talk about traditional wisdom and folk remedies and whether they have any scientific merit in preventing and treating infectious diseases.

You can read this book from beginning to end or use it as a reference for specific questions that you have. I hope that it will be helpful for a new generation of parents and that it will set the foundation for carefully evaluating the information we receive and carefully handling the situations we encounter every day. By applying what you learn from this book, you can reduce the frequency of infections in your family and better understand our fragile ecological balance with microbes.

Acknowledgments

As the poet George Seferis said, Our words are children of many people. This book would not have been possible without the help of many people during the course of my studies and work. The idea for this book started from a conversation with my mother, but its foundation was laid much earlier. I owe gratitude to my parents, who encouraged me along the path of knowledge and creation; my teachers all the way from elementary school to medical school and throughout my medical and research training, who introduced me to brave new worlds; my colleagues, with whom I continue to share knowledge; and my patients and their families, who continually offer me new challenges.

To my husband and sons, who were patient and forgiving of my absences for hours—day and night—as I spent my free time writing, I extend my heart-felt thanks. My special thanks to my father, Dr. Petros Kourtis, a general surgeon, to my husband, Dr. Alexander Kessler, an infectious diseases specialist, and my colleague Dr. Andi Shane, a pediatric infectious diseases specialist, who read various parts or all of my manuscript and provided thoughtful and useful comments. Jacqueline Wehmueller, executive editor at the Johns Hopkins University Press, believed in this project from the beginning, and Rowena Rae, my enthusiastic editor, made the book much more interesting to read. Finally, to my publishing team, which made the process, despite the hard work, exciting, I express my deep gratitude.

Keeping Your Child Healthy in a Germ-Filled World

When Germs and People Interact

AN INTRODUCTION

Germs, also called microorganisms or microbes, have been on Earth for more than three and a half billion years, making them the oldest living organisms. They are generally classified in four groups:

1. Bacteria are single-cell organisms that are just a few thousandths of a millimeter in size.

2. Viruses are infectious agents—technically not even organisms, because they can only multiply within other organisms—and are much smaller than bacteria.

3. Fungi are a type of plant and include microscopic yeasts and molds.

4. Parasites are organisms that live in or on a host organism and include microscopic single-cell protozoa and larger, nonmicroscopic parasites such as the helminths (worms).

Germs that cause diseases are labeled pathogenic. In reality, though, less than 1 percent of all germs cause disease in humans. About 100 billion bacteria live on our skin, and another 100 billion in our mouth. Our intestinal tract is covered by almost 100 trillion bacteria. Far from making us ill, these bacteria are beneficial to us. For example, many bacteria, such as some species of Lactobacillus, live in our intestines and help us to digest food, destroy pathogenic bacteria, fight against cancer cells, and produce necessary vitamins. The body’s immune system helps us to survive in the sea of microbes by learning, in infancy, to differentiate harmless and harmful bacteria. Thus, our immune system recognizes that the former are to be tolerated and the latter attacked, and, most of the time, the immune system does so quickly and effectively.

Germs and Humans throughout History

Although so few germs cause diseases, the pathogenic (disease-causing) germs, not surprisingly, are the ones we hear about most frequently. Pathogenic germs have caused infectious diseases in humans for millennia, possibly since the time of the first civilizations. Evidence of infections has been found in prehistoric humans, who may even have used natural remedies against them. For example, in the intestine of the Iceman, a frozen mummy found on the mountains of northern Italy and believed to have lived between 3300 and 3100 BC, scientists found the eggs of a parasite, Trichuris. They also discovered among the Iceman’s possessions the fruit of a birch fungus, which contains substances toxic to intestinal parasites. Perhaps prehistoric humans had identified this fungus as antiparasitic and were using it as a remedy.

There is no question that infectious diseases have played a central role in human history. Smallpox, described in ancient Egyptian and Chinese texts, is an infectious disease that has had a particularly large impact. Many researchers believe that over the centuries smallpox has caused more deaths than all other infectious diseases combined. The disease was eradicated from the world through a massive and coordinated immunization program against the smallpox virus; the last case occurred in 1977. To date, smallpox is the only human infectious disease that has been eliminated.

Malaria, mentioned in Egyptian texts and described in detail by Hippocrates, has also had a huge impact. Transmitted through the bite of mosquitoes that carry a parasite called Plasmodium, malaria was a scourge during the Roman Empire. Today, many swamps, where mosquitoes breed, have been drained, so malaria seldom occurs in Europe and North America. However, it continues to kill millions of people in the world’s tropical regions, and given the climate changes anticipated for the future, malaria is likely to expand into areas that today are not considered tropical, just as West Nile virus infection and dengue fever have.

Bubonic plague, another dreaded infectious disease, was spread in Europe, Africa, and the Middle East by fleas carried on rodents that arrived in merchant caravans from Mongolia. In the fourteenth century, bubonic plague killed 20 million people in Europe alone, earning it the label black death. Plague is caused by a bacterium transmitted to humans from a fleabite; the fleas become infected when they bite infected rodents, such as rats. Today, this disease is rare, but it does still occur.

Tuberculosis, caused by a mycobacterium and spread through the air, is an ancient disease that has plagued humans throughout history; indeed, evidence of it has been found in prehistoric skeletons and in Egyptian mummies dating from the fourth millennium BC. Romanticized in the eighteenth and nineteenth centuries and linked to artistic talent and temperament, tuberculosis nevertheless caused millions of deaths until antibiotics were discovered in the mid-twentieth century and higher standards of hygiene, nutrition, and living conditions emerged. Tuberculosis remains the leading cause of death worldwide from a curable infectious disease, and the new mycobacterial strains are more dangerous because they have become resistant to many antibiotics.

Influenza, or the flu, is another example of an infectious disease with a large impact on human history. Widespread epidemics, called pandemics, of flu have occurred several times during the twentieth century. The most severe flu pandemic, in 1918–19, caused between 20 million and 40 million deaths worldwide. There have been more flu pandemics over the intervening years, and we recently went through another one, the H1N1 pandemic, which was not as severe as others have been.

The human immunodeficiency virus (HIV), which leads to AIDS, has caused a new pandemic. In 2008 alone, HIV/AIDS killed about 2 million people worldwide, and another 33 million were living with the virus.

People’s Perceptions: How We Think about Germs

In the 1960s and 1970s, many scientists believed that modern medicine had defeated infectious diseases. In the two previous decades, the 1940s and 1950s, scientists discovered antibiotics and produced many new vaccines. This golden era of antibiotics and virology coincided with the development of insecticides and with tremendous progress in food preservation technologies. All these advances meant that many infectious diseases, which had previously threatened human health, appeared to have been defeated or controlled. In addition, with refrigeration widely used and modern methods in place for food production and processing, many people thought that hygiene was obsolete and redundant, and they stopped teaching their children about basic hygiene practices.

Humankind seemed to be less vulnerable to infections than ever before. In 1962, the microbiologist McFarlane Burnet, a Nobel laureate, prefaced a new edition of his book Natural History of Infectious Disease with at times one feels that to write about infectious diseases is almost to write of something that has passed into history. Today, with the benefit of hindsight, this statement appears complacent and arrogant. Indeed, in the past few years, scientists have come to recognize two different phenomena, both of which have radically changed the way we perceive germs.

The first phenomenon is the appearance of new germs and the reappearance of old ones that were on the verge of disappearing. The new germs include the avian flu and swine flu viruses, the severe acute respiratory syndrome (SARS) virus, the West Nile virus, the parasite Cryptosporidium, the bacterium Legionella, and, of course, HIV, the AIDS virus. About thirty new pathogenic germs have appeared in the last thirty years! Infectious diseases that have reappeared after having been controlled include poliomyelitis, tuberculosis, malaria, and a series of infections caused by germs that have developed resistance to antibiotics, an example of which is methicillin-resistant Staphylococcus aureus (MRSA).

We should not be surprised, because the genetic makeup of germs, like all living organisms, continually evolves as germs multiply. Thus, germs are able to infect other animal species, become less susceptible to antibiotics, and alter their response to a host’s immune defenses. Lately, these changes are occurring much more frequently. The worrisome acceleration in the rate at which germs are evolving results from a combination of factors, all related to human changes. We have adopted new behaviors, new methods of food production and processing, and new modes of rapid transportation, all of which promote the transmission and spread of germs. Advances in medical treatments and some new diseases have led to longer survival of patients with weakened immune defenses and greater vulnerability to infections.

Both the human population and the ease of global travel have increased greatly, leading to humans encroaching on more and more of the planet. Urbanization, industrialization, and changes in farming and animal husbandry have led to humankind destroying some ecosystems and altering the ecologic relationships of many others. As a result, pressure is put on germs, and this pressure causes them to evolve. Even medical and public health practices have pushed germs to evolve. A prime example is the overuse of antibiotics, which has contributed to a great problem in medicine today—difficult-to-treat infectious diseases caused by germs that have become resistant to antibiotics.

Other human-induced factors are also significant. Increases in both the exotic animal trade and forest destruction have led to greater opportunities for animal germs to jump to humans. From time to time, when the combination of pressures is just right, a previously harmless germ can evolve into one that is pathogenic for humans, as likely happened with the viruses that cause AIDS, SARS, and avian flu. Wars, natural disasters, and economic and political upheaval all affect the status of germs and infectious diseases. For example, economic and political changes in the early 1990s that brought about the collapse of public health systems in eastern Europe allowed dangerous diseases that had been quelled, like diphtheria, to resurface.

The World Health Organization (WHO) estimated that in 2004 alone, infectious diseases were responsible for over 10 million deaths worldwide, making infections the primary cause of fatalities in the world. While the number of deaths from infectious diseases has decreased in developed countries, the total number of infections has not changed. What have changed are the types of infections. For example, cholera and typhoid fever were prominent one hundred years ago, whereas today, there are more viral infections and recently emerged infections, like those caused by the bacteria Campylobacter and Legionella, the parasite Cryptosporidium, and HIV. The developing world still struggles with bacterial, viral, parasitic, and fungal infections that have become less common in developed countries but that continue to take the lives of millions of children and adults every year.

The second phenomenon that has become apparent recently is the large increase in the frequency of allergic conditions (asthma and other allergies) and autoimmune diseases (such as lupus, some types of arthritis, type 1 diabetes, and ulcerative colitis). The reasons behind these increases are not well understood, but some scientists have suggested that extreme cleanliness and antibiotic overuse (both in people and in animals) may be responsible.

A theory called the hygiene hypothesis proposes that our immune systems need a certain level of germs in the environment to be educated not to overreact to environmental stimuli. The proponents of this theory claim that a lack of germs, because of either a high level of hygiene or the excessive use of antibiotics and vaccinations, may have caused immune systems to become misguided and confused, resulting in the appearance of more allergies and autoimmune disorders in Western societies. In other words, the war that we declared against germs may have caused collateral damage to humans.

Many people simplified the hygiene hypothesis and declared that antibiotics, vaccines, and excessive cleanliness are enemies. Books and newspaper articles proliferated with titles like Let Your Children Be Dirty. I discuss the hygiene hypothesis in detail in Part II of this book, but suffice it here to say that harmful results of misinformation have already appeared. In the United States and in some European countries, more and more parents have stopped vaccinating their children. As a result, diseases that had almost disappeared, such as measles, pertussis (whooping cough), and mumps, have now staged a comeback.

Thus, these two phenomena make it clear that we cannot disregard germs; we still have much to learn about them and their interactions with humans. What does the future hold? We cannot (and we would not want to) destroy all germs, but we can lessen the harmful consequences of some that cause infections, while maximizing the benefits that our coexistence with others offers to our health and our children’s health. As parents, we have the essential role of protecting our children in a safe yet sensible way and of teaching them how to protect themselves as they navigate their lives through the microbial world.

PART I

Which Germs Where?

1

I’m Hungry!

FOOD-BORNE GERMS AND FOOD PREPARATION SAFETY

As parents, we are naturally concerned about the quality of food our children eat. Food provides the necessary energy and nutrients for children to survive and grow, but food can also harbor germs that make people ill. No parent would knowingly give a child contaminated food, yet food poisoning occurs in children, and adults, all too frequently. Most of the time, these food poisoning incidents are entirely preventable by following a few rules about food storage and preparation, as well as being aware of the risks associated with certain foods and locales.

In this chapter, I focus on the microorganisms that can be found in food and the risks these microbes pose to children. You will find a quick look at food-borne illness in table 1.1. I do not discuss the effects of preservatives, additives, or potentially toxic substances like pesticides or fertilizers that may be found in foods, nor do I discuss food allergies. In a later chapter, however, I describe the role of diet in the development of a child’s immune system, and I explore whether there is scientific truth in promoting certain substances as ingredients that strengthen the immune system.

What Are Food-Borne Germs and Where Do They Come From?

Typically, germs are microorganisms, or microbes, and include bacteria, viruses, parasites, and fungi. As I discussed in the book’s introduction, most germs are not harmful to humans. Some germs, however—called pathogenic germs, or pathogens—cause disease. A food-borne germ, therefore, is a pathogenic bacterium, parasite, or virus that is transmitted in food and causes illness in a person who eats the food. A person can also become ill from ingesting toxins, which are chemical substances produced by bacteria. Some bacteria in food will not cause illness themselves, but their toxins do. I use the general term food poisoning to identify a food-borne illness, regardless of whether the cause is a germ or a toxin.

The most common cause of food poisoning is a bacterium called Staphylococcus, often shortened to staph. Staph bacteria are found on many people’s skin and hands and may cause skin infections such as boils, cellulitis, or abscesses. If someone who handles food is a staph bacteria carrier, the bacteria or their toxins can get on the food being prepared. Most staph food poisonings occur with foods high in protein, such as cooked meat, poultry, and fish, dairy products, mayonnaise, potato salad, and cream-based desserts. The symptoms of staph food poisoning start within only a few hours of consuming the contaminated food. The affected person will have symptoms of nausea, vomiting, and abdominal pain, which usually resolve in a few hours (three to four hours in babies; six to eight hours in older children and adults).

Several other germs frequently cause food-borne illnesses:

• Salmonella bacteria are usually thought of in connection with foods like raw meat, raw or undercooked eggs, and unpasteurized milk, but they can also be found on fruits and vegetables. Thorough cooking destroys Salmonella. The bacteria can be transmitted to people from animals as well, particularly