Dr. Leigh Frame, PhD is Director of Integrative Medicine at George Washington School of Medicine and Health Sciences in Washington DC. Dr. Frame received her PhD in Human Nutrition, as well as a Master of Health Science degree in Molecular Microbiology and Immunology, from the Johns Hopkins Bloomberg School of Public Health. In this episode we discuss a range of topics including: the role of placebo groups and the different types we see in nutrient supplementation trials, potential ethical issues, and the development of research ethics. Show notes available at sigmanutrition.com/epsiode396/