WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!NAD+ for Brain Health: https://innovativemedicine.com/DAVE and save 20%Apple Cider Vinegar Benefits: https://paleovalley.com/DAVE, use code DAVE to get 15% off your first orderNon-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesIN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll learn about semaglutide, a new weight loss drug that’s been getting a lot of attention. Highly respected obesity expert Dr. Robert F. Kushner joins the show to talk about new research findings. He was part of a team that published semaglutide study results in the New England Journal of Medicine this past year. Looking into semaglutide, typically used for Type 2 Diabetes, showed that it also reduced body weight.We talk about how you might use semaglutide, both from an aging perspective and from a weight loss perspective. You look at risk reward for everything you can do, and then you decide what's going to work best for you. There's some interesting knowledge to be gained from the research on semaglutide.Here’s the short version of how it works: “Semaglutide mimics our naturally occurring hormone called GLP-1,” explains Dr. Kushner. “When you give it back to a person in pharmacologic doses or high doses, but it mimics what we normally have, it augments or highlights this feeling of, "You know what, I am really not as hungry as I was before. I'm more full than I was before, so I don't need as much food." It's actually the change in appetite that causes a weight loss that we see with this kind of a drug.”A clinician, educator and researcher, Dr. Kushner has spent his decades-long career on adult weight management for adults. Board certified in both internal medicine and nutrition, he maintains a medical practice, teaches students and medical professionals, and presents around the world. He’s written more than 250 original articles, as well as reviews, books and medical book chapters.He’s Medical Director of the Center for Lifestyle Medicine at Northwestern Medicine in Chicago; a professor of Medicine in the Division of Endocrinology and a professor of Medical Education at Northwestern University Feinberg School of Medicine.This episode’s conversation includes the role of lifestyle in weight management. It’s shortsighted to view semaglutide as a wonder drug isolated from diet, exercise and even mental health. It’s all related. And new understanding of obesity as a disease and its biological drivers helps the search for lasting solutions, including training for healthcare professionals.Listen on to find out more about semaglutide and six factors that might be causing your weight gain or making it difficult for you to lose weight.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.