Pain relief after surgery is a major headache as we don't have a lot of effective, and safe, options. Opioids in particular, like morphine, are very addictive and cause hundreds of thousands of deaths globally each year, and so doctors are desperate for alternatives. Now, scientists at the University of Buffalo have developed a long-lasting, local painkiller that can be injected into the site of injury to specifically prevent pain-transmitting nerve cells, or neurons, from passing on their painful messages to the brain. It works by stopping a process called endocytosis; this is where cells... Like this podcast? Please help us by supporting the Naked Scientists