Food Scientist and Registered Nutritionist, Kriben Govender (Honours Degree in Food Science & Technology) has an insightful conversation with Chief Scientific Officer of Microbiome Labs, Kiran Krishnan on How to build a resilient microbiome, metabolic endotoxemia (leaky gut), the negative impact of lipopolysaccharides (LPS), the diabetes pandemic, probiotics for optimal health, spore-based probiotics, postbiotics, butyrate and acne control, keystone bacteria in the gut and much more        Bio:    Kiran Krishnan is a Research Microbiologist and has been involved in the dietary supplement and nutrition market for the past 17 years. He comes from a strict research background having spent several years with hands-on R&D in the fields of molecular medicine and microbiology at the University of Iowa.  He is currently involved in 9 novel human clinical trials on probiotics and the human microbiome. Kiran is also on the Scientific Advisory Board for 5 companies in the industry. Kiran offers his extensive knowledge and practical application of the latest science on the human microbiome as it relates to health and wellness.       Topics discussed:   Kiran’s origin story What does good gut health look like? The concept of “resilience” in gut health What about different dietary regimes like paleo, vegan, carnivore etc? Human evolution of omnivores Gut sensitivity in the modern world How to foster resilience The concept of “Holobiome" Living in an antibiotic laden world Exposure from personal care products Maximising exposure to environmental microbes Allergies, Asthma and the microbiome Diversity of diet like our ancestors Spore based bacteria Metabolic endotoxemia (leaky gut) and chronic disease  Lipopolysaccharides, Gram-Positive and Gram-Negative Bacteria Sepsis and bacteraemia signalling LPS and Chronic inflammation, Rheumatoid Arthritis, Anxiety and Depression, Alzheimer's  LPS toxicity and bacterial types LPS and Diabetes Risk LPS mechanism on impairing blood sugar modulation The impact of C-section on gut microbiome composition  Antibiotics and the microbiome What is a probiotic organism? Where do probiotics come from? The origin of Spore based probiotics What are spore-based bacteria? https://www.nourishmeorganics.com.au/collections/probiotics/products/megasporebiotic-spore-based-probiotic-antioxidant-60-capsules The gastric barrier, bile salts and pancreatic enzymes  Short Chain Fatty Acids, Postbiotics and Metformin Butyrate and insulin sensitivity Butyrate and acne control  Oligosaccharide based prebiotics- FOS, GOS, XYLO https://www.nourishmeorganics.com.au/collections/prebiotics/products/megaprebiotic-150g Keystone Species in the Microbiome: Akkermansia, Faecalibacterium, Bifidobacteria, Ruminocococus  The benefits of dead bacteria (biological response modifiers), BLP1, Micro RNA, Microvesicles  Intra- kingdom communication and gene expression The importance of subspecies classification and associated health benefits The science of postbiotics and AMUC   Megasporebiotic and Leaky Gut https://www.nourishmeorganics.com.au/collections/probiotics/products/megasporebiotic-spore-based-probiotic-antioxidant-60-capsules     Brought to you by:   Nourishme Organics- The Gut Health Superstore   Check out our range of clinically proven probiotic supplements including Microbiome Labs Megasporebiotic:   https://www.nourishmeorganics.com.au/collections/probiotics   Use code guthealthgurus for 10% off     Connect with Kiran Krishnan   Website- https://microbiomelabs.com/       Connect with Kriben Govender:    Facebook- https://www.facebook.com/kribengee/ Instagram- https://www.instagram.com/kribengovender/ Youtube- https://www.youtube.com/c/Nourishmeorganics?sub_confirmation=1 Gut Health Gurus Facebook Group: https://www.facebook.com/groups/nourishmeorganics/ Deuterium Depletion Support Facebook Group: https://www.facebook.com/groups/347845406055