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Episode References:

Froestl W, Muhs A, Pfeifer A. Cognitive enhancers (nootropics). Part 1: drugs interacting with receptors. J Alzheimers Dis. 2012;32(4):793-887. doi:10.3233/JAD-2012-121186
Nehlig A, Daval JL, Debry G. Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res Brain Res Rev. 1992;17(2):139-170. doi:10.1016/0165-0173(92)90012-b
Institute of Medicine (US) Committee on Military Nutrition Research. Caffeine for the Sustainment of Mental Task Performance: Formulations for Military Operations. Washington (DC): National Academies Press (US); 2001. 2, Pharmacology of Caffeine. Available from: https://www.ncbi.nlm.nih.gov/books/NBK223808/
Hansen PB, Schnermann J. Vasoconstrictor and vasodilator effects of adenosine in the kidney. Am J Physiol Renal Physiol. 2003;285(4):F590-F599.
Faudone G, Arifi S, Merk D. The Medicinal Chemistry of Caffeine. J Med Chem. 2021;64(11):7156-7178. doi:10.1021/acs.jmedchem.1c00261oi:10.1152/ajprenal.00051.2003
Gessi S, Merighi S, Fazzi D, Stefanelli A, Varani K, Borea PA. Adenosine receptor targeting in health and disease. Expert Opin Investig Drugs. 2011;20(12):1591-1609. doi:10.1517/13543784.2011.627853
Spilling the Beans: How Much Caffeine is Too Much? United States Food and Drug Administration. Updated Dec 12, 2018. Accessed Aug 4, 2022. https://www.fda.gov/consumers/consumer-updates/spilling-beans-how-much-caffeine-too-much#:~:text=For%20healthy%20adults%2C%20the%20FDA,it%20(break%20it%20down).
Brain Basics: Understanding Sleep. National Institute of Neurological Disorders and Stroke. Updated July 25, 2022. Accessed Aug 4, 2022. https://www.ninds.nih.gov/health-information/patient-caregiver-education/brain-basics-understanding-sleep