Rochelle P. Walensky, MD, MPH, of Harvard Medical School and Massachusetts General Hospital returns to JAMA's COVID-19 Q&A to provide an update on developments in the pandemic. She is a signatory of the recent John Snow Memorandum emphasizing the importance of public health interventions to manage the spread of COVID-19. Recorded October 22, 2020. Related Article(s): Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions