On this week’s episode of Fast Facts - Perio Edition, Katrina Sanders, we are continuing the conversation around periodontitis as a manifestation of systemic disease discussing patients that present with Papillon-Lefèvre.   Quotes:    “Patients who present with Papillon-Lefèvre are oftentimes characterized by patients who have hyperkeratosis of their tissue. Most specifically, they present with hyperkeratosis of their palms and the bottoms of their feet.”   “These individuals can start to experience disease processes onset of periodontal disease that is frequent and recurring that oftentimes results in pus in the tissues and so with these individuals, we can oftentimes see that they are prematurely losing their teeth associated with the sequelae of periodontal disease.” Resources:   DentistRX: https://www.dentistrx.com  More Fast Facts: https://www.ataleoftwohygienists.com/fast-facts/    Katrina Sanders Website: https://www.katrinasanders.com  Katrina Sanders Instagram: https://www.instagram.com/thedentalwinegenist/    Sources:   Papapanou, P. N., Sanz, M., Buduneli, N., Dietrich, T., Feres, M., Fine, D. H., ... & Tonetti, M. S. (2018). Jepsen S, Caton JG, Albandar JM, Bissada NF, Bouchard P, Cortellini P, Demirel K, de Sanctis M, Ercoli C, Fan J, Geurs NC, Hughes FJ, Jin L, Kantarci A, Lalla E, Madianos PN, Matthews D, McGuire MK, Mills MP, Preshaw PM, Reynolds MA, Sculean A, Susin C, West NX, Yamazaki K. Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018 Jun;89 Suppl 1:S237-S248. doi: 10.1002/JPER.17-0733. PMID: 29926943.