11 min listen
Simvastatin Pharmacology
FromReal Life Pharmacology - Pharmacology Education for Health Care Professionals
Simvastatin Pharmacology
FromReal Life Pharmacology - Pharmacology Education for Health Care Professionals
ratings:
Length:
15 minutes
Released:
Jul 23, 2020
Format:
Podcast episode
Description
Simvastatin use has declined over time due to more potent statins being available and due to numerous drug interactions.
Grapefruit juice can inhibit CYP3A4 which will increase the concentrations of simvastatin.
Genetic variations in SLCO1B1 can lead to patients being more susceptible to simvastatin toxicity.
Simvastatin is a lipophilic statin. I discuss why this is important and how it might impact clinical decisions.
Grapefruit juice can inhibit CYP3A4 which will increase the concentrations of simvastatin.
Genetic variations in SLCO1B1 can lead to patients being more susceptible to simvastatin toxicity.
Simvastatin is a lipophilic statin. I discuss why this is important and how it might impact clinical decisions.
Released:
Jul 23, 2020
Format:
Podcast episode
Titles in the series (100)
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