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Episode 003 - Dr Morgan Langille – microbiome bioinformatics, DNA sequencing, metagenomics

Episode 003 - Dr Morgan Langille – microbiome bioinformatics, DNA sequencing, metagenomics

FromInside Matters


Episode 003 - Dr Morgan Langille – microbiome bioinformatics, DNA sequencing, metagenomics

FromInside Matters

ratings:
Length:
108 minutes
Released:
Oct 20, 2022
Format:
Podcast episode

Description

Dr Morgan Langille, an expert in bioinformatics, talks about developing novel technologies and techniques that enable a better understanding of human-microbial interactions. 
 
Dr Langille discusses advances in the microbiome field as well as combining computer science and microbiology to lead to new therapeutics and diagnostics.
 
Episode Time Stamps

00:00 Intro
00:30, How Dr Langille got into the field of the microbiome
04:30, Gene duplication and reverse transcription
05:48, What is bioinformatics?
06:34, The evolution of bioinformatics 
09:30, Genomic islands
1:04 - Phages
14:30 Dr Langille’s first bioinformatics tool 
16:00 Bacterial genome libraries 
18:20 Extremeophilic bacteria
19:00 Will there be bugs in space
21:42 Bacteria on Mars 
22:15 Human microbiome diversity 
23:30 Number of human cells vs microbes in the body 
25:00 Genomic diversity within the microbiome 
28:00 Perfect bioinformatics 
33:40 Bioinformatics and microbiome research
34:37 Short read vs long read sequencing 
45:30 Shotgun metagenomics 
48:00 Bioinformatic tool development 
1:01:00 Differences in bioinformatic tools and impact on research 
1:06:00 Solutions to current technology challenges in bioinformatics
1:10:06 Tools that Morgan has developed 
1:08:05 PICRUSt - bioinformatic tool 
1:18:35 Jarvis - bioinformatic tool 
1:24:00 Talent wars for bioinformatics 
1:26:36 Machine learning and AI
1:32:51 Colorectal cancer and AI 
1:36:35 Is blood sterile?
1:38:00 What does the future of medicine look like 
1:40:51 DIY FMT

 
Released:
Oct 20, 2022
Format:
Podcast episode

Titles in the series (48)

The gut health show – conversations with the most forward-thinking minds in health, fitness, science, nutrition and business. In-depth discussions about how our gut microbiome impacts our health, well-being, mood and more. Inside Matters was conceived by microbiome expert Dr James McIlroy as a platform to raise awareness of the importance of the gut microbiome. Our aim is to inspire and educate listeners around the world about the importance of gut health, equipping them with the knowledge they need to transform their lives for the better.