Research has uncovered many benefits of fasting. In this episode, 2 medical experts describe the different types of fasting, the physiology of fasting, the research associated with a special type of fast, and the clinical applications of the fasting mimicking diet. Listeners will learn how to enhance the efficacy and sustainability of their fasting protocols. About the Experts James Kelley, MD, MBA, is the medical science liaison of L-Nutra. His background is in the development of early-stage medical and biotechnology, in addition to working with and educating physicians, nurses, and other healthcare professionals. Kelley completed his M.D. at The Ohio State University, and was the inaugural research fellow at the Ohio Health Research and Innovation Institute. He finished his MBA at the University of Southern California Marshall School of Business. He has worked with the USC Alfred Mann Institute for Biomedical Engineering, the Lloyd Grief Center for Entrepreneurial Studies, and the Stevens Institute of Technology. He holds a bachelor’s degree in cell biology from the University of Virginia and completed his neuroscience masters coursework at Miami University. Prior to joining the L-Nutra team, he was the head of Inventor Services at The Innovation Institute, a partnership with the Cleveland Clinic Innovations group focused on developing and commercializing new and innovative healthcare solutions. Deepa Verma MD, AIHM, is a double board-certified physician in family and integrative medicine. She is a graduate of Rutgers Medical School (formerly Robert Wood Johnson) and a faculty speaker for health organizations such as The American Academy of Anti-Aging Medicine (A4M), Cutera, and Age Management Medicine Group (AMMG), just to name a few. In 2013, she founded a healing-oriented practice, Synergistiq Integrative Health, after experiencing some personal challenges and feeling unfulfilled treating patients traditionally. She believes that challenges are presented not as obstacles, but as stepping stones. In addition to working in private practice, Verma is a blogger and TV personality, having made appearances on NBC, ABC, PBS, and Lifetime TV. She is a regular guest on Bay News 9. Verma’s passion for healthy living resonates in everything she does personally and professionally. She understands the angst and frustrations that patients feel when they are sick and tired of feeling tired and sick. To learn more about her integrative/anti-aging practice and expertise, visit drdeepaverma.com and synergistiqhealth.com. About the Sponsor As research grows in this area of health, prolonged fasting is becoming more widely accepted as a legitimate means of managing weight and aid in the management of risk for metabolic diseases. At the same time, it is clear that fasting can be challenging and uncomfortable, and therefore, it is important that it is done in proper and healthy ways. As fasting trends, such as intermittent fasting, gain popularity, the extended fasting periods (without food) can lead to a myriad of negative side effects, including irritability and the likelihood of overeating during the “eating” period. While most people think of fasting in terms of the common definition of fasting, which is the abstinence of food or drink, cellular fasting is linked to downregulation of the nutrient-sensing pathways and upregulation of stress resistance mechanisms. Nutrient sensing pathways are sensors that are activated in the presence of adequate nutrients (amino acids, glucose, energy). ProLon has been scientifically developed to avoid triggering the three key Nutrient Sensing Pathways namely: PKA (Carbohydrate Pathway), IGF-1 (Protein Pathway), and mTOR (Amino Acids Pathway). Culminating more than 20 years of research and discoveries on fasting made at the University of Southern California (USC), L-Nutra is a nutrition technology company using breakthrough science to enhance human health, promote healthy aging, and support overall well-be