In the 1970s, a savvy CEO named Dwayne Andreas hit on an idea: take surplus corn from America's heartland, process it into a sweetener, and start selling it to anyone who would buy, all in the name of patriotism. Within a decade, high fructose corn syrup dominated the U.S. sweetener market; today, American diets are saturated with sweeteners, including cane sugar, high fructose corn syrup, and dozens of others. But Andreas wasn't reinventing the wheel. He was just taking the next step in a 400-year journey that took sugar from a rare delicacy for the wealthy to an inextricable part of our lives, our culture, and our bodies. A journey that began on the brutal sugar plantations of Haiti and eventually went global, confronting us all with an impossible moral dilemma. In this episode, we journey across centuries and continents to visit the people who've schemed — and those who've suffered — to bring us sweetness.