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Episode: 42 - Machine Learning Informatics for Antibody Discovery

Episode: 42 - Machine Learning Informatics for Antibody Discovery

FromThe Chain: Protein Engineering Podcast


Episode: 42 - Machine Learning Informatics for Antibody Discovery

FromThe Chain: Protein Engineering Podcast

ratings:
Length:
36 minutes
Released:
Nov 8, 2022
Format:
Podcast episode

Description

Charlotte Deane, professor of structural bioinformatics at the University of Oxford and upcoming speaker at the 14th Annual PEGS Europe Conference in Barcelona, joins moderator Brandon DeKosky, assistant professor of chemical engineering at the Massachusetts Institute of Technology, to discuss the use of machine learning in antibody structure prediction. In this episode, Deane talks about her lab's AI tools for high-throughput prediction pipelines and why collecting general antibody property data will produce better models. She also speaks about the importance of using and building publicly available data sets and her thoughts on what it will take to finally generate a complete antibody design from a computer. Links from this episode:  University of Oxford Department of Statistics SAbDAb: The Structural Antibody Database PEGS Europe The Critical Assessment of protein Structure Prediction (CASP) 
Released:
Nov 8, 2022
Format:
Podcast episode

Titles in the series (65)

The Chain explores the lives, careers, research, and discoveries of protein engineers and scientists, the impact their work is having on the field, and where the industry is headed. Tune in to stay up-to-date on the newest advancements and to hear the stories that are impacting the world of biologics.