Mast cell activation (MCAS), Ehlers-Danlos syndrome (EDS), and postural orthostatic tachycardia syndrome (POTS) are three often debilitating conditions on their own, but it seems they're likely connected to one another. Join me and Dr. Weinstock as he explains the symptoms of these conditions, how they're linked, and what the future looks like for treatment. Even if you're only dealing with MCAS or POTS, this episode is worth a listen. Featured Studies  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352424/ https://pubmed.ncbi.nlm.nih.gov/26976734/ https://pubmed.ncbi.nlm.nih.gov/34618688/ https://pubmed.ncbi.nlm.nih.gov/32824107/ https://pubmed.ncbi.nlm.nih.gov/30022117/ https://pubmed.ncbi.nlm.nih.gov/36337620/ https://pubmed.ncbi.nlm.nih.gov/25640519/ https://pubmed.ncbi.nlm.nih.gov/34496250/ https://pubmed.ncbi.nlm.nih.gov/35636614/ https://pubmed.ncbi.nlm.nih.gov/31421665/ https://pubmed.ncbi.nlm.nih.gov/34441978/ https://pubmed.ncbi.nlm.nih.gov/27741023/ https://pubmed.ncbi.nlm.nih.gov/33629149/ https://pubmed.ncbi.nlm.nih.gov/30118241/#:~:text=Conclusions%3A%20This%20study%20clearly%20confirms,controlled%20trial%20is%20thus%20warranted. https://pubmed.ncbi.nlm.nih.gov/35663980/ https://pubmed.ncbi.nlm.nih.gov/27436071/ https://pubmed.ncbi.nlm.nih.gov/23666445/ https://pubmed.ncbi.nlm.nih.gov/29183244/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537261/ Related Resources What is POTS: https://drruscio.com/pots/ Choosing an MCAS diet: https://drruscio.com/mcas-diet/  To contribute to the MCAS documentary: https://ldnresearchtrust.org/documentary-fundraiser  More about LDN: https://ldnresearchtrust.org/what-is-low-dose-naltrexone-ldn  Courses, free guides, and more: https://drruscio.com/resources?utm_source=youtube&utm_medium=link&utm_campaign=drruscio.com_resources   Timestamps 00:00 Intro  01:06 What is the “triad”? 02:58 MCAS, POTS, & EDS defined 14:33 What are effective therapeutics for healing? 17:20 Approach to MCAS: Step 1 18:14 The importance of mental health 27:32 How these immune symptoms connect to gut health 33:18 Where Dr. Weinstock starts with stomach distension  36:32 Immunoglobulins 38:50 Sodium butyrate  39:42 The low FODMAP diet for dysbiosis 42:30 Effective therapies for POTS & EDS 47:39 Low-dose naltrexone   Get the Latest Updates Facebook - https://www.facebook.com/DrRusciodc  Instagram - https://www.instagram.com/drrusciodc  Pinterest - https://www.pinterest.ca/drmichaelrusciodc   DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment. Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g  *Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.