Andrea Valente spent the past 20+ years building global clinical trial tech organizations and technologies. Recently, Andrea was named CEO of ClinOne, a company that offers a virtual clinical trial platform for patients.  Jennifer Peters had an idea to streamline payments between clinical trial sponsors and investigators, so she co-founded a company called Greenphire in 2008 which was acquired for $1.1 billion in 2021. She is also Board Chair of ClinOne. In this episode we discuss the relationship between patients and sites, the role of protocol design on participant engagement/retention, the technology adoption cycle, empowering patients by empowering sites, platforms vs interoperability, and the value of more women in leadership roles in clinical research.