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Choosing an absorption model (Ep. 24)

Choosing an absorption model (Ep. 24)

FromClinical Pharmacology Podcast with Nathan Teuscher


Choosing an absorption model (Ep. 24)

FromClinical Pharmacology Podcast with Nathan Teuscher

ratings:
Length:
24 minutes
Released:
Apr 22, 2024
Format:
Podcast episode

Description

Today’s show discussed approaches for modeling absorption profiles. I discussed the rationale behind modeling absorption and then described some common models. These included first-order absorption, zero-order absorption, transit compartments, distributed delay, Weibull, and zero/first order absorption. I also provided my recommendations on how to model absorption.

Links discussed in the show:

Distributed delay modeling in PK and PD
Modeling biphasic formulation of methylphenidate
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Copyright Teuscher Solutions LLC
All Rights Reserved
Released:
Apr 22, 2024
Format:
Podcast episode

Titles in the series (27)

I discuss clinical pharmacology and pharmacometrics topics from the perspective of drug development scientists. I share my expertise and knowledge about designing and conducting clinical pharmacology studies and discuss how to analyze the data using the most effective approaches. I draw from my experience of over 20 years working in drug development organizations and consultancies.