Per- and polyfluoroalkyl substances, a class of chemicals known as PFAS, are often called “forever chemicals” because of how long they persist in the environment. They are prevalent in drinking water and have been linked to negative health outcomes. A slew of cleantech start-ups are cropping up with the aim of breaking down and destroying PFAS molecules. In this episode of C&EN Uncovered, reporter Britt Erickson explores the technologies behind these companies and the competition among them. C&EN Uncovered, a project from C&EN’s podcast, Stereo Chemistry, offers a deeper look at subjects from recent stories. Check out Britt’s cover story on the destruction techniques for these “forever chemicals” at cenm.ag/foreverchemicals. Cover photo: Argon gas plasma, which can break down PFAS, on the surface of liquid water Subscribe to Stereo Chemistry now on Apple Podcasts, Spotify, or wherever you listen to podcasts.   A transcript of this episode will be available soon at cen.acs.org. Credits Executive producer: Gina Vitale C&EN Uncovered host: Craig Bettenhausen Reporter: Britt Erickson Audio editor: Ted Woods Copyeditor: Bran Vickers Story editor: Michael McCoy Episode artwork: Courtesy of Selma Mededovic Thagard/Clarkson University Music: “Hot Chocolate,” by Aves Contact Stereo Chemistry: Contact us on social media at @cenmag or email cenfeedback@acs.org.