In this episode of The Skin Science Podcast, Thomas M. Hitchcock, Ph.D., Chief Science Officer, speaks with Angela Wilson McDonald, Global VP, Education and Customer Success, and Brian Jones, Ph.D., VP, R&D and Biomedical Innovation, about biome boosted microneedling and the clinical study to support it. The Skin Science Podcast is intended to provide listeners with information regarding various topics in the field of skin science. None of the content in this podcast should be interpreted or construed as professional or medical advice. Further, the views and opinions expressed by guests are their own and do not represent those of Crown Laboratories, Inc., and the appearance of any guest on the podcast does not imply an endorsement of the guest or any particular entity they represent.0:00 Introduction2:50 Before/after photo from Crown "Biome-boosted microneedling" clinical study 6:34 Story behind the SkinPen + BIOJUVE biome-boosted microneedling study 9:50 Treatment of acne scars13:08 Optimal environment for skin remodeling 16:40 Philosophy of the BIOJUVE regimen19:00 How topicals influence skin physiology 23:03 Study design and rationale28:20 Results 30:30 Before/after photos 33:20 Opportunity to enhance microneedling results 38:25 Improvement beyond acne scarring40:20 Remodeling process43:50 Closing remarksAlqam, M. L., Jones, B. C., & Hitchcock, T. M. (2023). Topical application of skin biome care regimen containing live cultures and ferments of Cutibacterium acnes defendens strain XYCM42 and the impact on clinical outcomes following microneedle-induced skin remodeling. Journal of Clinical and Aesthetic Dermatology, 16(12), 18–30. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10729805/pdf/jcad_16_12_18.pdf